Interestingly, also reduction of atrial K2P3.1 (TASK-1) expression was linked to AF as in a dog model of postoperative AF, a phosphorylation dependent downregulation of K2P3.1 (TASK-1) was reported [50] and CREM-TG AF mice display atrial downregulation of K2P3.1 (TASK-1) in conjunction with massive atrial dilatation and scarring [16]. This evidence concerns the gene KCNK3 and atrial fibrillation.