MAPK3 and allergic disease: It is also known that phosphatidylinositol 3-kinase (PI3K)/AKT, MAPKs such as c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase 1/2 (Erk1/2), p38), and nuclear factor-κB (NF-κB) are involved in cytokine production from MCs during allergy [44,45,46,47].