Specific genetic mutations of VCP have been associated with a multisystem degenerative disorder termed inclusion body myopathy, which is associated with Paget’s disease of bone and frontotemporal dementia (IBMPFD), encompassing muscle, brain, and bone, and with other diseases such as Parkinsonism and dilated cardiomyopathy (DCM) [8,9,10,11,12]. This evidence concerns the gene VCP and inclusion body myopathy with Paget disease of bone and frontotemporal dementia.