ANO1 and cystic fibrosis: In the same manner, we can probably expect not only an ANO1 activation in the airways but also in multiple tissues affected by CF and in which ANO1 is expressed, such as the male reproductive tracts, the liver, and gallbladder, the proximal digestive tract, and the gastrointestinal tract (https://www.proteinatlas.org; accessed on October 2021).