PALM2AKAP2 and myocardial infarction: The fact that AKAP2 KO in cardiomyocytes negatively impacts cardiac function in MI mice without inducing deleterious effects in sham operated animals suggests that this cardioprotective anchoring protein is mainly mobilized in stressed hearts undergoing MI and does not contribute, in the short-term, to preserve baseline cardiac function (Figure 1, Figure 3 and Figure 6 and Supplementary Materials Figure S5).