AGT and cardiomyopathy: Interestingly, acetyltransferase p300 is involved in Klf15 deficiency-induced cardiomyopathy and aortapathy as evidenced by the observation that acetyltransferase p300 inhibitor curcumin significantly ameliorates AngII-induced aortapathy and cardiomyopathy-related pathologies in Klf15 knockout mice [64].