Nobre et al. [88] demonstrated one distinct NG+/Nestin+ MSC in the bone marrow and its abundance resulted in intensified secretion of TGF-β2 and BMP7 and activation of common downstream p27, p38, and SMAD through binding with TGFBRIII and BMPRII, respectively, inducing cascade accounting for breast cancer latency in bone marrow. This evidence concerns the gene BMP7 and breast carcinoma.