However, although the infusion dose to 3.2 × 107 CD56+ cells/dose/mouse (maximal dose of 4 × 107 cells/dose/mouse, total three doses) does not exactly match with the GvHD reaction, it is most likely a potentially toxic dose that could cause GvHD due to it containing a high dose of T cells in final product. The gene discussed is NCAM1; the disease is graft versus host disease.