SMARCA1 and thyroid cancer: Two other key FGs are the histone methyltransferases (HMTs) and the SWItch/Sucrose NonFermenting (SWI/SNF) chromatin remodeling complex, and mutations in these FGs are reported to be more frequent in advanced forms of thyroid cancers than in classic PTCs [11,12], albeit their clinical prognostic significance has not been established.