CASC8 and medulloblastoma: Recently, a comparison of Asian and Caucasian medulloblastoma cohorts by Luo et al. revealed 31 novel gene fusions among all medulloblastoma subgroups [14], including recurrent gene fusions such as RAP1A–TMIGD3 with identical breaking points in two WNT MBs and one group 3 MB, PVT1–CASC8 with different breaking points in two group 3 MBs and one group 4 MB, and three more gene fusions in at least two medulloblastoma patients affecting only the Asian cohort [14].