Molecular genomic profiling of tumor tissue led us to describe the concomitant high grade amplification of six loci located at: 2p25.3 (log2 ratio = 4.47) containing MYT1L and TSSC1 genes and the long intergenic non-protein coding RNA LOC730811; 2p25.2 (log2 ratio = 4.38) containing CMPK2, RSAD2, and RNF144A genes; 2p25.1 (log2 ratio = 3.758) containing the long intergenic non-protein coding RNA LOC339788; 2p25.1–p24.3 (log2 ratio = 4.05) containing GREB1, NTSR2, and LPIN1 genes; 2p24.3 (log2 ratio = 4.36) containing NBAS gene; 2p24.3 (log2 ratio = 4.29) containing MYCN gene (Figure 1A). The gene discussed is CMPK2; the disease is neoplasm.