RNF144A, LPIN1, and MYT1L genes, therefore, behave as tumor suppressor genes; in particular, the pan neuron-specific transcription factor MYT1L exerts an important function in neuronal differentiation [20,43], and its overexpression could lead to a differentiation of NB cells with a beneficial effect for patients’ outcome. Here, RNF144A is linked to neoplasm.