In reference to glycans, mucins, which are high-molecular-weight proteins that are extensively coated with O-glycans, seem interesting tumor-specific targets based on their high expression on tumor tissues, low abundance in healthy tissues and pivotal roles in carcinogenesis [18,19] Especially, transmembrane mucin-1 (MUC1) and secreted mucin-5AC (MUC5AC), which are both, directly and indirectly, involved in tumor progression via their truncated sTn glycans, are considered promising targets for PDAC targeting [18]. This evidence concerns the gene MUC5AC and neoplasm.