The selection of the optimal positivity threshold and the correlative and prognostic associations of CSF-1R on carcinoma cells and macrophages were first assessed in the training cohort (n = 1183) of the BC Cancer series (Supplementary Tables S2–S4 and Supplementary Figure S3) before confirming the results in the validation cohort, presented in this section. This evidence concerns the gene CSF1R and breast cancer.