FSCN1 and osteosarcoma: Moreover, in vitro data also demonstrated the role of FSCN1 in inducing cancer cell migration by promoting filopodia formation and epithelial-mesenchymal transition (EMT) [68] in various cancer cells, including ovarian [37], oral [53], hypopharyngeal [69], osteosarcoma [70], and pancreatic cancer cells [41].