In PDAC cell lines, DCLK1-IN-1 was unable to impair PATU-8998T 3D spheroid growth in ultra-low attachment plates [17], but in RCC, we quantified a potent and consistent reduction in this property in both ACHN and CAKI-1 spheroids in ultra-low attachment conditions (Figure 3B). Here, DCLK1 is linked to renal cell carcinoma.