We further validated the expression of CTNND1 in cell lines and found that breast epithelial cell line MCF-10A expressed higher CTNND1 than breast cancer cell lines in which bone metastatic MDA-MB-231-1833 cell line (an MDA-MB-231 variant with high metastatic bone tropism) displayed the lowest CTNND1 expression (Figure 3A,B). This evidence concerns the gene CTNND1 and breast carcinoma.