CD4 and Kaposi's sarcoma: In the French ANRS CO4 FHDH cohort, PLHIV with undetectable plasma HIV-RNA and restored immunity (i.e., CD4 ≥ 500/mm3 for at least 2 years) still had a 35-fold higher risk of KS compared to the general population (standardized incidence ratio (SIR) = 35.4; 95% CI 18.3–61.9) [3].