In another study, FAAH inhibition in combination with 2-methyl-2′-fluoro-anandamide (Met-F-AEA) was shown to lead to cell cycle arrest in the G0/G1 phase and apoptosis in lung cancer cells, mediated by a reduction in epidermal growth factor receptor (EGFR) activation and downstream signalling pathways [122]. This evidence concerns the gene EGFR and lung carcinoma.