For example, a targeting nanogel comprised of HA (to target CD44 receptor in cancer cells) and EGCG (to bind to protein) was assembled for the intracellular delivery of granzyme B. The study reported the increased cytotoxicity against CD44 presenting HCT-116 cells indicating the potential use of HA and EGCG as protein carriers for cancer treatment [73]. This evidence concerns the gene GZMB and cancer.