Recent work on endometrial cancer showed that FGFR inhibitors (Infigratinib, AZD4547 and PD173074) caused mitochondrial depolarisation, cytochrome c release and impaired mitochondrial respiration in two FGFR2-mutant endometrial cancer cell lines (AN3CA and JHUEM2). This evidence concerns the gene CYCS and endometrial cancer.