In accordance with this notion, the knockdown of RBP-J interacting and tubulin-associated protein (RITA) was shown to impair the FA turnover, migration and invasion in breast cancer cells as well as fibroblasts by interacting with α-actinin, lipoma preferred partner (LPP) and further stabilizing the MT cytoskeleton [43]. The gene discussed is RBPJ; the disease is breast carcinoma.