MTOR and neoplasm: Furthermore, CBD induces autophagy and cell death under oxidative stress conditions in cancer and results in impaired endothelial cell proliferation, migration, and tumor microvasculture by inhibiting protein kinase B (Akt), ERK, PI3K, mammalian target of rapamycin (mTOR) signaling, adenylate cyclase, J-Jun, NF-kB activity, actin stress fibers and focal adhesion formation, and FAK and JNK signaling [4,5,6,7,8].