WNT1 and neoplasm: This is the case of the wingless-type MMTV integration site family member 1 (WNT1)-driven breast oncogenesis [135] in which the haploinsufficiency of BECN1 upregulates WNT1 signaling and TNF receptor superfamily member 11a (TNFRSF11A)—nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) pathway to sustain tumor growth, and that was mediated by the cadherin-catenin complex [136].