When these five genes were considered individually, only the presence of TP53 (p = 0.071, Fisher’s exact test) and SRSF2 (p = 0.071, Fisher’s exact test) mutations appeared to be potentially linked to disease progression, and TP53 (p = 0.081) applied to MPN in particular. The gene discussed is SRSF2; the disease is myeloproliferative disorder.