VEGFA and breast cancer: During the first, second and third years after surgery, the VEGF concentrations (85.48 pg/mL, 80.34 pg/mL and 81.01 pg/mL) in patients with stage II BC were statistically significantly lower compared to the preoperative levels (p = 0.001, p < 0.001, p = 0.001), which is similar to the CA 15-3 concentrations.