Numerous novel proinflammatory proteins are associated with atherosclerosis and cardiovascular risk, including chemokine C-C motif ligand 4 (CCL4), chemokine C-C motif ligand 7 (CCL7), sortilin (SORT1), myeloperoxidase (MPO), interleukin 1 receptor-like 1 (IL1RL1), and growth differentiation factor 15 (GDF15) [7]. The gene discussed is GDF15; the disease is atherosclerosis.