Moreover, several blood markers have been related directly or indirectly, acting through the increase in the low-grade chronic pro-inflammatory state to an increase in cardiovascular risk: high levels of glucose, glycated hemoglobin (HbA1c) and diabetes mellitus [6], high levels of total cholesterol and specifically low-density-lipoprotein (LDL) cholesterol [7], low levels of vitamin D [8], or high levels or C-reactive protein (CRP) [9] are some examples. The gene discussed is CRP; the disease is diabetes mellitus.