These proteins include the following: SOD and TDP-43 in ALS; amyloid-beta, tau, and p75 neurotrophin receptors in Alzheimer’s disease; synuclein in Parkinson’s disease; HTT in Huntington’s disease; androgen receptors in spinal and bulbar muscular atrophy; prion in prion-related diseases; ataxins in spinocerebellar ataxias [88,89], myocilin in glaucoma [90], and apparently recoverin and arrestin in AMD [33,91]. Here, TARDBP is linked to early-onset autosomal dominant Alzheimer disease.