In addition, Alk and Cxcl1 genes are exclusively downregulated in WT mice and it is noteworthy to mention that loss of function of both these genes is associated with reduced neurogenesis and alteration of behavioral measures, such as activity and anxiety levels [49,50,51], providing a further link between our molecular and phenotypic data in WT mice. This evidence concerns the gene CXCL1 and Anxiety.