The association between PODNL1 CpG methylation status and the three immunotherapeutic targets in oligodendroglioma depended on the specific CpG sites, with no association observed for cg26969888, significantly higher expression of only PD-L1 in low methylated cg07425555, significantly higher expression of PD-L1 and CTLA4 in low methylated cg24354933, and significantly higher expression of all three targets in low methylated cg18547299 (Figure 7(Di–Div)). Here, CD274 is linked to oligodendroglioma.