CASP3 and cervical cancer: When studying the relationship between sensitivity to nedaplatin (NDP) and immunohistochemical expression of such biological factors in cervical cancer as Ki-67, p53, Bcl-2, Bax, cleaved caspase-3, and COX-2, it was found that low or negative expression of p53, Bcl-2, and COX-2 and high or positive expression of cleaved caspase-3 were significantly correlated with high sensitivity to NDP, whereas there were no significant differences in Ki-67, Bax, or ERCC1 expression between the low and high sensitivity groups.