CDKN2A and cervical carcinoma: Thus, a review study conducted on the basis of analysis of 28 publications and devoted to the assessment of the immunohistochemical expression of Ki-67, p16, and p53 in precancerous lesions and cervical cancer indicates that high expression, especially of p16 and Ki-67, is observed in more severe lesions, while in normal cervical epithelium it is minimal or absent [32].