CD40 and neoplasm: Our gene expression data showed CD40 expression was slightly higher in CRCs with CSF1R genotype A_G compared to genotype A_A (log2 fold of change: 0.04849 and p = 0.772221), and our prior study demonstrated the number of macrophages was significantly higher in tumor tissues with the genetic background of CSF1R c.1085 genotype A_A compared to genotype A_G [8].