In another cross-sectional comparative study, Fonseca Camarillo et al. evaluated the expression levels of IL-36α, IL-36β, IL-36γ, IL-36Ra, and IL-38 genes, their producing cells, and their correlation with clinical activity in IBD and non-inflamed non-IBD persons (as a control group) by reverse transcriptase-polymerase chain reaction (RT-PCT) and double-staining IHC techniques. This evidence concerns the gene IL36B and inflammatory bowel disease.