IL1F10 and arthritic joint disease: In this study, inhibitory features of IL-38 in streptococcal cell wall (SCW)-induced arthritis and monosodium urate (MSU) crystal-induced arthritis were recognized by a reduction in joint swelling, inflammatory cell influx, and synovial levels of several pro-inflammatory cytokines, clearly indicating the potential abilities of IL-38 as an acceptable seroimmunobiomarker and immunotherapeutic target for patients with arthritis [125].