SERPINF2 and thrombotic thrombocytopenic purpura: Several animal studies also investigated the role of α2AP in pulmonary embolism, ischaemic stroke, thrombotic thrombocytopenic purpura (TTP), and arterial thrombosis, in which α2AP was shown to be involved in the formation and removal of venous thrombi in mice [55,56,57,58,59].