A 5-miRNA signature has been identified as predictive markers for EGFR mutation in NSCLC, namely miR-25, miR-122, miR-195, miR-21, and miR-125b in tumor tissues and plasma, where plasma levels of has-miR-125b expression in the patients were linked to disease-free survival, and overall survival, thereby acting as a prognostic marker [69]. This evidence concerns the gene EGFR and neoplasm.