Adhesion molecules such as VCAM-1 and ICAM-1 and chemokines such as MCP-1/JE and CXCL1/KC are important modulators in monocyte recruitment, rolling, and adhesion to the vascular endothelium and play a fundamental role in the pathogenesis of atherosclerosis [35,36,47]. The gene discussed is ICAM1; the disease is atherosclerosis.