It has been reported to inhibit ovarian cancer cell growth by inhibiting the secretion of the primary angiogenesis mediators, Akt, hypoxia-inducible factor 1-alpha (HIF-1α), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), and vascular endothelial growth factor (VEGF). The gene discussed is HIF1A; the disease is ovarian cancer.