ALB and cardiovascular disorder: Although reduced eGFR might be partially responsible for the higher CPP generation propensity in patients with cerebrovascular disease or myocardial infarction, the restriction of patient and control cohorts to the subjects having an eGFR >90 mL/min/1.73 m2 did not change the results, as cardiovascular disease patient cohorts still demonstrated higher CPP generation propensity, increased serum ionised calcium, and reduced total protein and albumin levels.