PrPSc-like PrP (hereafter simply referred to as PrPSc) was constitutively produced in IAV/WSN-infected N2aC24 cells even after IAV/WSN infection was cleared during long culture [24], indicating that persistent IAV/WSN infection is not necessary for the constitutive conversion PrPC into PrPSc in the cells. Here, PRNP is linked to infection.