We further showed that the anti-IAV agent oseltamivir and anti-IAV mouse antisera blocked IAV/WSN infection of N2aC24 cells and prevented formation of PrPSc-like PrP in the cells [24], not only ruling out the possibility of the contamination of laboratory prions in the cell culture, but also confirming that IAV/WSN infection is essential for the conversion of PrPC into PrPSc-like PrP in the cells. The gene discussed is PRNP; the disease is early-onset parkinsonism-intellectual disability syndrome.