Among the genes associated with both AD and hypoglycemia, we have identified those that are promising for further study as drug targets (CCL2, CD40, CDKN1A, CYP3A4, FOS, HCRT, IGFBP2, IL6, MAP2, METAP2, NFE2L2, PARK7, SELP, SST, VEGFA and others). This evidence concerns the gene METAP2 and Alzheimer disease.