SLC7A11 and colorectal carcinoma: In addition, the benzopyran derivative 2-imino-6-methoxy-2H-chromene-3-carbothioamide (IMCA) prevents the growth of CRC cells by downregulating SLC7A11 through AMP-activated protein kinase (AMPK)/the mechanistic target of rapamycin complex I (mTORC1) signaling [105].