At the same time, C. perfringens infection sharply decreased the mRNA expression level of Mucin 2 in IPEC-J2 cells (p < 0.05), while it was effectively alleviated by preincubation with L. plantarum Lac16 (p < 0.05; Figure 4C). This evidence concerns the gene MUC2 and infection due to clostridium perfringens.