Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of insoluble forms of β-amyloid (Aβ) in plaques in extracellular spaces and in the walls of blood vessels as well as the aggregation of hyperphosphorylated protein tau in neurofibrillary tangles in neurons [1,2]. The gene discussed is MAPT; the disease is Alzheimer disease.