WNK3 and cancer: For more clarity on the proposed hypothetical model of how the PR may be involved in cancer proliferation, and how blocking the PR may help to provide significant clinical relief from the effects of cancer, Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5 provide a visual mechanism of the hypothetical ways that there may be interaction of the nuclear and membrane PRs and the production of immunomodulatory proteins.