Across 22 tumor types originating from various districts (genito-urinary, gastro-intestinal, gynecological, head and neck, brain, endocrine, pulmonary, etc.)(TCGA data), this region was co-amplified with PD-L1 in >80% of tumors with focal PD-L1 copy number gains (CNGs). Here, CD274 is linked to neoplasm.