PPARA and Stroke: Another PPAR-α/γ dual agonist, propane-2-sulfonic acid octadec-9-enyl-amide (N15), exhibited neuroprotective potential in mouse model of stroke via stimulation of PPAR-α/γ signaling and inhibiting the activation of the NF-κB, STAT3, and ERK1/2 signaling pathways [207].