TNFAIP3 and neoplasm: In contrast, Balkhi et al. revealed that miR-29, which has a complementary sequence of 3′ UTR of tumor-suppressive TNFAIP3 mRNA, was decreased in patients with sarcoma, and it directly bound to the RBPs HuR, inhibited the recruitment of RISC to the 3′ UTR of TNFAIP3 mRNA, and negatively regulated NFkB signaling, thereby suppressing tumorigenesis in sarcoma cells [37].