ELF3 was reported to inhibit invasion of oral squamous cell carcinoma [7]; however, its overexpression was reported to be associated with the promotion of tumor growth in lung [8], poor cancer prognosis in colorectal cancer [9], copy number gain in breast cancer [10], and reported to facilitate tumor cell growth and metastasis in NSCLC [11]. The gene discussed is ELF3; the disease is non-small cell lung carcinoma.