All the tested compounds (4, 5a–l) were found to inhibit the growth of the Bcl-2-expressing human cancer cell lines (MDA-MB-231, HeLa and KG1a) with low micromolar IC50 values, except 5c, which was inactive against the KG1A (Acute Myeloid Leukemia) cell line (Table 1). This evidence concerns the gene BCL2 and acute myeloid leukemia.