Marine, a herbal medicine derived from Sophora flavescens, induces anti-prostate cancer effects by activating GRP78, CHOP, and ATF4, phosphorylating eIF2α, and inhibiting the EMT process via the decrease of E-cadherin and the increase of N-cadherin and vimentin [60]. The gene discussed is HSPA5; the disease is Familial prostate cancer.